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mavorixafor will boost the stage or impact of codeine by impacting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a solid CYP2D6 inhibitor) is contraindicated with medicine which can be really depending on CYP2D6 for clearance.Intense Allergic Reactions. Dextromethorphan may trigger allergic reactions, that may be serious. Stop us